{"product_id":"histone-h4-k5-polyclonal-antibody-bs1662","title":"Histone H4 (K5) Polyclonal Antibody - BS1662","description":"\u003cp\u003eHistone H4 (K5) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS1662-50, BS1662-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: Histone proteins H3, H4, H2A, and H2B function as building blocks to package eukaryotic DNA into repeating nucleosome units that are folded in higher order chromatin fibers. The nucleosome is composed of an octamer containing a H3\/H4 tetramer and two H2A\/H2B dimers, surrounded by approximately 146 base pairs of DNA. A diverse and elaborate array of post-translational modifications including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation occurs on the N-terminal tail domains of histones. Methylation of position-specific lysine residues in histone N termini is a central modification for regμlating epigenetic transitions in chromatin. Each methylatable lysine residue can exist in a mono, di, or tri methylated state. Arginine resdiues can also by mono or di methylated.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Histone H4, HIST1H4A, H4\/A, H4FA, HIST1H4B, H4\/I, H4FI, HIST1H4C, H4\/G, H4FG, HIST1H4D, H4\/B, H4FB, HIST1H4E, H4\/J, H4FJ, HIST1H4F, H4\/C, H4FC, HIST1H4H, H4\/H, H4FH, HIST1H4I, H4\/M, H4FM, HIST1H4J, H4\/E, H4FE, HIST1H4K, H4\/D, H4FD, HIST1H4L, H4\/K, H4FK, HIST2H4A, H4\/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4\/O, H4FO, HIST4H4\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodification\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to the N-terminal of Human Ribosomal Histone H4.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB: 1:500~1:1000\u003cbr\u003e\nIHC: 1:50~1:200\u003cbr\u003e\nIF: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Histone H4 (K5) polyclonal antibody detects endogenous levels of Histone H4 protein.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 11 kDa\u003c\/p\u003e\n\n\u003cp\u003ePathway: Examples of Crosstalk Between Post-translational Modifications,\u003c\/p\u003e \n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: P62805\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45946223460531,"sku":"BS1662-50","price":274.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45946223493299,"sku":"BS1662-100","price":457.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_6ca33534-2486-4e91-ac84-9e0d75778258.jpg?v=1788363539","url":"https:\/\/afsbio.com\/products\/histone-h4-k5-polyclonal-antibody-bs1662","provider":"AFSBio Inc.","version":"1.0","type":"link"}