{"product_id":"histone-h4-mono-methyl-lys21-polyclonal-antibody-bt-ap10044","title":"Histone H4 (Mono Methyl Lys21) Polyclonal Antibody - BT-AP10044","description":"\u003cp\u003eHistone H4 (Mono Methyl Lys21) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP10044-20, BT-AP10044-50, BT-AP10044-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: Histone\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Histone H4\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P62805; Mouse: P62806; Rat: P62804\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Histone H4; H4K21ME1; HIST1H4A; H4\/A; H4FA; HIST1H4B; H4\/I; H4FI; HIST1H4C; H4\/G; H4FG; HIST1H4D; H4\/B; H4FB; HIST1H4E; H4\/J; H4FJ; HIST1H4F; H4\/C; H4FC; HIST1H4H; H4\/H; H4FH; HIST1H4I; H4\/M; H4FM; HIST1H4J; H4\/E; H4FE; HIST1H4K; H4\/D; H4FD; HIST1H4L; H4\/K; H4FK; HIST2H4A; H4\/N; H4F2; H4FN; HIST2H4; HIST2H4B; H4\/O; H4FO; HIST4H4; Histone H4\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 121504\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239168139443,"sku":"BT-AP10044-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239168172211,"sku":"BT-AP10044-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239168204979,"sku":"BT-AP10044-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_849afbd0-a5a4-4e6a-9f9e-6eeae6c69457.png?v=1769390060","url":"https:\/\/afsbio.com\/products\/histone-h4-mono-methyl-lys21-polyclonal-antibody-bt-ap10044","provider":"AFSBio Inc.","version":"1.0","type":"link"}