{"product_id":"histone-h4-polyclonal-antibody-bt-ap04118","title":"Histone H4 Polyclonal Antibody - BT-AP04118","description":"\u003cp\u003eHistone H4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP04118-20, BT-AP04118-50, BT-AP04118-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HIST1H4A\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat, Monkey\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Histone H4 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 11367\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P62805; Mouse: P62806; Rat: P62804\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: HIST1H4A; H4\/A; H4FA; HIST1H4B; H4\/I; H4FI; HIST1H4C; H4\/G; H4FG; HIST1H4D; H4\/B; H4FB; HIST1H4E; H4\/J; H4FJ; HIST1H4F; H4\/C; H4FC; HIST1H4H; H4\/H; H4FH; HIST1H4I; H4\/M; H4FM; HIST1H4J; H4\/E; H4FE; HI\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 121504\/554313\/8294\/8359\/8360\/8361\/8362\/8363\/8364\/8365\/8366\/8367\/8368\/8370; Mouse: 100041230; Rat: 100360950\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240371183795,"sku":"BT-AP04118-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240371216563,"sku":"BT-AP04118-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240371249331,"sku":"BT-AP04118-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_21136719-d974-4e30-8c38-69278baf599d.png?v=1769407488","url":"https:\/\/afsbio.com\/products\/histone-h4-polyclonal-antibody-bt-ap04118","provider":"AFSBio Inc.","version":"1.0","type":"link"}