{"product_id":"hla-dpa1-monoclonal-antibody-bt-mca3755","title":"HLA-DPA1 Monoclonal Antibody - BT-MCA3755","description":"\u003cp\u003eHLA-DPA1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3755-50, BT-MCA3755-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HLA-DPA1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 2B1A10\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2a\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: HLA-DPA1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human HLA-DPA1 (AA: 29-209) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 29.3kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P20036\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: DPA1, PLT1, HLADP, HLASB, DP(W3), DP(W4), HLA-DPA, HLA-DP1A, HLA-DPB1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3113\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238504521907,"sku":"BT-MCA3755-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238504554675,"sku":"BT-MCA3755-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_3689cf7e-11f7-4fb2-970a-9f6d27d4af8c.png?v=1769381921","url":"https:\/\/afsbio.com\/products\/hla-dpa1-monoclonal-antibody-bt-mca3755","provider":"AFSBio Inc.","version":"1.0","type":"link"}