{"product_id":"hla-dpb1-polyclonal-antibody-e-ab-52719","title":"HLA-DPB1 Polyclonal Antibody - E-AB-52719","description":"\u003cp\u003eHLA-DPB1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-52719-60, E-AB-52719-120, E-AB-52719-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: HLA-DPB1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: D6S221E; DMA; DMB; DP beta 1; DP beta 1 chain; DP(W4) beta chain; DPB 1; DPB1; DPB1; DRB; H2Ea; HLA class II histocompatibility antigen; HLA class II histocompatibility antigen DM beta chain ; HLA class II histocompatibility antigen; DP beta 1 chain; HLA class II histocompatibility antigen; DP(W4) beta chain; HLA DMB; HLA DP1A; HLA DPB1; HLA SB alpha chain; HLA-A; HLA-A histocompatibility type; HLA-DP; HLA-DP histocompatibility type; beta-1 subunit; HLA-DP1B; HLA-DPB; HLA-DPB1; HLADM; HLADP1B; HLASB; HLASB histocompatibility type; Human MHC class II HLA SB alpha; LA class II histocompatibility antigen DP alpha 1 chain; Major histocompatibility complex class II; Major histocompatibility complex class II DP alpha 1; Major histocompatibility complex class II DP beta 1; Major histocompatibility complex; class I; A; MHC class II antigen DMB; MHC class II antigen DPB1; MHC class II DP3 alpha; MHC class II DPA1; MHC class II HLA-DP-beta-1; MHC DPB1; MHC HLA DPB1; PLT1; Primed lymphocyte test 1; RING6; RING7\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Immunology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P04440\u003c\/p\u003e\n\n\u003cp\u003eBackground: HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.9 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Fusion protein of human HLA-DPB1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IHC 1:20-1:100, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 29 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43143969472691,"sku":"E-AB-52719-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43143969505459,"sku":"E-AB-52719-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43143969538227,"sku":"E-AB-52719-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_51e932ba-e5bf-402f-a81e-17d50a606eb6.png?v=1710244536","url":"https:\/\/afsbio.com\/products\/hla-dpb1-polyclonal-antibody-e-ab-52719","provider":"AFSBio Inc.","version":"1.0","type":"link"}