{"product_id":"hla-f-monoclonal-antibody-bt-mca2862","title":"HLA-F Monoclonal Antibody - BT-MCA2862","description":"\u003cp\u003eHLA-F Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2862-50, BT-MCA2862-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HLA-F\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 3D10H2\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2b\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: HLA-F\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human HLA-F (AA: 22-305) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 39kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P30511\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: HLAF, CDA12, HLA-5.4, HLA-CDA12\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3134\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238382297267,"sku":"BT-MCA2862-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238382330035,"sku":"BT-MCA2862-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_678b54c9-e059-4d4e-8a71-a4620d4057b9.png?v=1769379604","url":"https:\/\/afsbio.com\/products\/hla-f-monoclonal-antibody-bt-mca2862","provider":"AFSBio Inc.","version":"1.0","type":"link"}