{"product_id":"hmg-1-acetyl-lys12-polyclonal-antibody-bt-ap04139","title":"HMG-1 (Acetyl Lys12) Polyclonal Antibody - BT-AP04139","description":"\u003cp\u003eHMG-1 (Acetyl Lys12) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP04139-20, BT-AP04139-50, BT-AP04139-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: HMGB1 encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. High mobility group box 1 plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of HMGB1 have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HMGB1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: HMG-1 (Acetyl Lys12) Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 24894\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P09429; Mouse: P63158; Rat: P63159\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3146; Mouse: 100862258; Rat: 25459\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240372461747,"sku":"BT-AP04139-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240372494515,"sku":"BT-AP04139-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240372527283,"sku":"BT-AP04139-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_76870a60-3eb8-441f-84d6-ef0b5609060b.png?v=1769407505","url":"https:\/\/afsbio.com\/products\/hmg-1-acetyl-lys12-polyclonal-antibody-bt-ap04139","provider":"AFSBio Inc.","version":"1.0","type":"link"}