{"product_id":"hmg-2-polyclonal-antibody-bt-ap04146","title":"HMG-2 Polyclonal Antibody - BT-AP04146","description":"\u003cp\u003eHMG-2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP04146-20, BT-AP04146-50, BT-AP04146-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: HMGB2 encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that high mobility group protein B2 is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HMGB2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: HMG-2 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 24034\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P26583; Mouse: P30681; Rat: P52925\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: HMGB2; HMG2; High mobility group protein B2; High mobility group protein 2; HMG-2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3148; Mouse: 97165; Rat: 29395\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240373149875,"sku":"BT-AP04146-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240373182643,"sku":"BT-AP04146-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240373215411,"sku":"BT-AP04146-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b4d65e49-782b-4a39-8494-8d648271e143.png?v=1769407514","url":"https:\/\/afsbio.com\/products\/hmg-2-polyclonal-antibody-bt-ap04146","provider":"AFSBio Inc.","version":"1.0","type":"link"}