{"product_id":"hmgb1-polyclonal-antibody-bs7131","title":"HMGB1 Polyclonal Antibody-BS7131","description":"\u003cp\u003eHMGB1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS7131-50, BS7131-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P09429\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eHMGB1 Polyclonal Antibody-BS7131\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:500~1:2000\u003cbr\u003e\nIHC\/IF: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Research suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture, including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, ATF-2, c-Jun and members of the NFκB family to activate transcription.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: HMGB1 polyclonal antibody detects endogenous levels of HMGB1 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~25 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of HMGB1 polyclonal antibody, Immunohistochemistry (IHC) analysis of HMGB1 polyclonal antibody in paraffin-embedded Human Embryo Brain tissue.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: High mobility group protein B1; High mobility group protein 1; HMG-1; HMGB1; HMG1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant full length Human HMGB1.\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42962813255859,"sku":"BS7131-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42962813288627,"sku":"BS7131-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_3958c85e-eb97-4b72-8623-ee010e6bbe8f.jpg?v=1705319085","url":"https:\/\/afsbio.com\/products\/hmgb1-polyclonal-antibody-bs7131","provider":"AFSBio Inc.","version":"1.0","type":"link"}