{"product_id":"hnf-3α-β-γ-rabbit-polyclonal-antibody-es4054","title":"HNF-3α\/β\/γ Rabbit Polyclonal Antibody - ES4054","description":"\u003cp\u003eHNF-3α\/β\/γ Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES4054-50, ES4054-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: FOXA1, HNF3A, TCF3A, Hepatocyte nuclear factor 3-alpha, HNF-3-alpha, HNF-3A, Forkhead box protein A1, Transcription factor 3A, TCF-3A, FOXA2, HNF3B, TCF3B, Hepatocyte nuclear factor 3-beta, HNF-3-beta, HNF-3B, Forkhead box protein A2, Transcription factor 3B, TCF-3B, FOXA3, HNF3G, TCF3G, Hepatocyte nuclear factor 3-gamma, HNF-3-gamma, HNF-3G, Fork head-related protein FKH H3, Forkhead box protein A3, Transcription factor 3G, TCF-3G\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human FOXA1 around the non-acetylation site of Lys265. AA range:231-280\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: HNF-3α\/β\/γ\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: HNF-3α\/β\/γ Polyclonal Antibody detects endogenous levels of HNF-3α\/β\/γ protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Highly expressed in prostate and ESR1-positive breast tumors, Overexpressed in esophageal and lung adenocarcinomas,\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 50kD\u003c\/p\u003e\n\n\u003cp\u003eFunction: Function: Transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes\u003cbr\u003e\nOnline Information: Hepatocyte nuclear factors entry,Similarity: Contains 1 fork-head DNA-binding domain\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Nucleus\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: FOXA1\/FOXA2\/FOXA3\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Hepatocyte nuclear factor 3-alpha\/Hepatocyte nuclear factor 3-beta\/Hepatocyte nuclear factor 3-gamma\u003c\/p\u003e\n\n\u003cp\u003eMouse Gene ID: 15375\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: P35582\u003c\/p\u003e\n\n\u003cp\u003eRat Gene ID: 25098\u003c\/p\u003e\n\n\u003cp\u003eRat SwissProt Number: P23512\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46316539773107,"sku":"ES4054-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46316539805875,"sku":"ES4054-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies_d75295e2-ffc1-4e0f-a3e7-87715c8983a9.jpg?v=1793190507","url":"https:\/\/afsbio.com\/products\/hnf-3%ce%b1-%ce%b2-%ce%b3-rabbit-polyclonal-antibody-es4054","provider":"AFSBio Inc.","version":"1.0","type":"link"}