{"product_id":"hnf-4alpha-acetyl-lys106-polyclonal-antibody-bt-ap10092","title":"HNF-4Alpha (Acetyl Lys106) Polyclonal Antibody - BT-AP10092","description":"\u003cp\u003eHNF-4Alpha (Acetyl Lys106) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP10092-20, BT-AP10092-50, BT-AP10092-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Cardiovascular; Developmental biology; Epigenetics and nuclear signaling; Metabolism; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HNF4A\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Hepatocyte nuclear factor 4-alpha\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P41235; Mouse: P49698; Rat: P22449\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Hepatocyte nuclear factor 4-alpha;HNF-4-alpha;Nuclear receptor subfamily 2 group A member 1;Transcription factor 14;TCF-14;Transcription factor HNF-4; Hepatocyte nuclear factor 4-alpha; HNF-4-alpha; Nuclear receptor subfamily 2 group A member 1; Transcription factor 14; TCF-14; Transcription factor HNF-4\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3172\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239169253555,"sku":"BT-AP10092-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239169286323,"sku":"BT-AP10092-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239169319091,"sku":"BT-AP10092-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_3a1b1c2b-5d0c-477a-9cb6-cb708160d5ba.png?v=1769390075","url":"https:\/\/afsbio.com\/products\/hnf-4alpha-acetyl-lys106-polyclonal-antibody-bt-ap10092","provider":"AFSBio Inc.","version":"1.0","type":"link"}