{"product_id":"hnf-4alpha-gamma-polyclonal-antibody-bt-ap04159","title":"HNF-4Alpha\/Gamma Polyclonal Antibody - BT-AP04159","description":"\u003cp\u003eHNF-4Alpha\/Gamma Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP04159-20, BT-AP04159-50, BT-AP04159-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Hepatocyte nuclear factor 4-alpha\/Hepatocyte nuclear factor 4-gamma encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HNF4A\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: HNF-4alpha\/gamma Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 52785\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P41235; Mouse: P49698; Rat: P22449\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: HNF4A; HNF4; NR2A1; TCF14; Hepatocyte nuclear factor 4-alpha; HNF-4-alpha; Nuclear receptor subfamily 2 group A member 1; Transcription factor 14; TCF-14;Transcription factor HNF-4; HNF4G; NR2A2; Hepa\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3172; Mouse: 15378; Rat: 25735\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240373772467,"sku":"BT-AP04159-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240373805235,"sku":"BT-AP04159-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240373838003,"sku":"BT-AP04159-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_645d3925-02d7-4b06-96c8-c6a64ea6dc10.png?v=1769407523","url":"https:\/\/afsbio.com\/products\/hnf-4alpha-gamma-polyclonal-antibody-bt-ap04159","provider":"AFSBio Inc.","version":"1.0","type":"link"}