{"product_id":"hnf1alpha-phospho-ser247-rabbit-polyclonal-antibody-bt-ap03026","title":"HNF1Alpha (Phospho-Ser247) Rabbit Polyclonal Antibody - BT-AP03026","description":"\u003cp\u003eHNF1Alpha (Phospho-Ser247) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP03026-20, BT-AP03026-50, BT-AP03026-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5andapos;-GTTAATNATTAAC-3andapos;. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HNF1A\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: HNF1alpha\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P20823; Mouse: P22361; Rat: P15257\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: HNF1α;Ser247; Hepatocyte nuclear factor 1-alpha; HNF-1-alpha; HNF-1A; Liver-specific transcription factor LF-B1; LFB1; Transcription factor 1; TCF-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6927; Mouse: 21405; Rat: 24817\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45238999023795,"sku":"BT-AP03026-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45238999056563,"sku":"BT-AP03026-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238999089331,"sku":"BT-AP03026-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_724c3909-4b6e-439c-a7b8-97af075ccbd1.png?v=1769387755","url":"https:\/\/afsbio.com\/products\/hnf1alpha-phospho-ser247-rabbit-polyclonal-antibody-bt-ap03026","provider":"AFSBio Inc.","version":"1.0","type":"link"}