{"product_id":"hnf1b-monoclonal-antibody-bt-mca2687","title":"HNF1B Monoclonal Antibody - BT-MCA2687","description":"\u003cp\u003eHNF1B Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2687-50, BT-MCA2687-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HNF1B\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 4H5C2\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: HNF1B\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human HNF1B (AA: 23-132) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 61.3kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P35680\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: T2D, FJHN, HNF2, LFB3, RCAD, TCF2, HPC11, LF-B3, MODY5, TCF-2, VHNF1, ADTKD3, HNF-1B, HNF1beta, HNF-1-beta\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 6928\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238516875443,"sku":"BT-MCA2687-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238516908211,"sku":"BT-MCA2687-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_2585dc5b-d029-4e68-abb8-524b2228879d.png?v=1769382013","url":"https:\/\/afsbio.com\/products\/hnf1b-monoclonal-antibody-bt-mca2687","provider":"AFSBio Inc.","version":"1.0","type":"link"}