{"product_id":"hnmt-polyclonal-antibody-e-ab-64679","title":"HNMT Polyclonal Antibody - E-AB-64679","description":"\u003cp\u003eHNMT Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-64679-60, E-AB-64679-120, E-AB-64679-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: HNMT\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: HNMT; HMT; HNMT-S1; HNMT-S2; MRT51\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer,Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P50135\u003c\/p\u003e\n\n\u003cp\u003eBackground: In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human HNMT\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 6kDa\/14kDa\/33kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 33kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146342760627,"sku":"E-AB-64679-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146342793395,"sku":"E-AB-64679-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146342826163,"sku":"E-AB-64679-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_78b2660f-c8c4-4b2d-890b-eb0b0f2ec9cb.png?v=1710293903","url":"https:\/\/afsbio.com\/products\/hnmt-polyclonal-antibody-e-ab-64679","provider":"AFSBio Inc.","version":"1.0","type":"link"}