{"product_id":"hnrnpμl2-polyclonal-antibody-bs62389","title":"hnRNPμl2 Polyclonal Antibody - BS62389","description":"\u003cp\u003ehnRNPμl2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS62389-50, BS62389-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: Heterogeneous nuclear ribonucleoprotein U-like protein 2, is a mμltifunctional protein and previous studies have implicated it in the modμlation of p53 transcriptional activity, although this has been rather poorly understood. Resμlts presented here demonstrate that hnRNPμl-1 represses p53 transcriptional activity and negatively regμlates p21 levels. This is consistent with the depletion of hnRNPμl-1 leading to an increase in cells arrested in G1\/S. Together these resμlts confirm that hnRNPμl-1 acts as a p53 co-repressor with specific cellμlar targets.\u003c\/p\u003e \n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Heterogeneous nuclear ribonucleoprotein U-like protein 2, Scaffold-attachment factor A2, SAF-A2, HNRNPμl2, HNRPμl2\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodification\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to Human hnRNPμl2.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB:1:500~1:1000 IHC:1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003ePurification: The protein was purified from E.coli and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: hnRNPμl2 polyclonal antibody detects endogenous levels of hnRNPμl2 protein.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 90 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: Q1KMD3\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45938452103347,"sku":"BS62389-50","price":274.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45938452136115,"sku":"BS62389-100","price":457.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_7d54f7f7-895a-4faa-805b-93c7ca9b170c.jpg?v=1788296274","url":"https:\/\/afsbio.com\/products\/hnrnp%ce%bcl2-polyclonal-antibody-bs62389","provider":"AFSBio Inc.","version":"1.0","type":"link"}