{"product_id":"hnrnp-k-y280-polyclonal-antibody-bs2997","title":"hnRNP K (Y280) Polyclonal Antibody-BS2997","description":"\u003cp\u003ehnRNP K (Y280) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS2997-50, BS2997-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Heterogeneous nuclear ribonucleoprotein K; hnRNP K; Transformation up-regulated nuclear protein; TUNP; HNRNPK; HNRPK\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P61978\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003cbr\u003e\nIHC: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: The majority of hnRNP proteins components are localized to the nucleus; however some shuttle between the nucleus and the cytoplasm, such as hnRNP K. hnRNP K, a 65 kDa protein, recruits a variety of molecular partners through two K homologous (KH) domains, which are required for protein-protein interactions. hnRNP K also contains several potential phosphorylation sites, including Ser 302, the major site of PKCd phosphorylation, which are thought to regulate various cellular functions, including sequence-specific DNA binding, transcription, RNA binding and nucleocytoplasmic shuttling.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: hnRNP K (Y280) polyclonal antibody detects endogenous levels of hnRNP K protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 58-62 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of hnRNP K (Y280) pAb at 1:1000 dilution\u003cbr\u003e\nLane 1: HCC827 whole cell lysate(40ug)\u003cbr\u003e\nLane 2: HEK293T whole cell lysate(20ug)\u003cbr\u003e\nLane 3: A549 whole cell lysate(40ug)\u003cbr\u003e\nLane 4: C6 whole cell lysate(40ug)\u003cbr\u003e\nLane 5: CT26 whole cell lysate(40ug)\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 250-300 of Human hnRNP K.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42911800885427,"sku":"BS2997-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42911800918195,"sku":"BS2997-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_1b178eb0-5612-4e37-938b-d4cf3ffbc142.jpg?v=1703179468","url":"https:\/\/afsbio.com\/products\/hnrnp-k-y280-polyclonal-antibody-bs2997","provider":"AFSBio Inc.","version":"1.0","type":"link"}