{"product_id":"hp-1α-mouse-monoclonal-antibody-5e3-ra11429","title":"HP-1α Mouse Monoclonal Antibody (5E3) - RA11429","description":"\u003cp\u003eHP-1α Mouse Monoclonal Antibody (5E3)\u003c\/p\u003e \n\n\u003cp\u003eSize: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA11429-50, RA11429-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: chromobox 5 (CBX5) Homo sapiens This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eApplications: IF\/ICC; WB; IHC-p\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 23468\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 22\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P45973\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45119038259379,"sku":"RA11429-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45119038292147,"sku":"RA11429-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b1106137-f36c-4fb2-a39d-24565030c582.png?v=1773344491","url":"https:\/\/afsbio.com\/products\/hp-1%ce%b1-mouse-monoclonal-antibody-5e3-ra11429","provider":"AFSBio Inc.","version":"1.0","type":"link"}