{"product_id":"hp-1alpha-mouse-monoclonal-antibody-5e3-bt-mca0050","title":"HP-1Alpha mouse Monoclonal Antibody (5E3) - BT-MCA0050","description":"\u003cp\u003eHP-1Alpha mouse Monoclonal Antibody (5E3)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-MCA0050-20, BT-MCA0050-50, BT-MCA0050-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Tags and; cell markers\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CBX5 HP1A\u003c\/p\u003e\n\n\u003cp\u003eApplications: IF, ICC, WB, IHC-p\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human,Mouse,Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Chromobox protein homolog 5\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P45973; Mouse: Q61686\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Chromobox protein homolog 5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 23468\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240028463283,"sku":"BT-MCA0050-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240028496051,"sku":"BT-MCA0050-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240028528819,"sku":"BT-MCA0050-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_2ec65d9b-c257-4f3f-b0d6-228217ba6063.png?v=1769402364","url":"https:\/\/afsbio.com\/products\/hp-1alpha-mouse-monoclonal-antibody-5e3-bt-mca0050","provider":"AFSBio Inc.","version":"1.0","type":"link"}