{"product_id":"hp1γ-polyclonal-antibody-ra26043","title":"HP1γ Polyclonal Antibody - RA26043","description":"HP1γ Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA26043-50, RA26043-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: chromobox 3 (CBX3) Homo sapiens At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011],\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/40000. Not yet tested in other applications.\n\nAlternative Names: CBX3; Chromobox protein homolog 3; HECH; Heterochromatin protein 1 homolog gamma; HP1 gamma; Modifier 2 protein\n\nApplications: WB; IHC-p; IF (paraffin section) ; ELISA\n\nSpecies Cross-Reactivity: Human; Mouse; Rat\n\nGeneID (Human): 11335\n\nProtein MW (KDa): 22\n\nSWISS: Q13185\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121336639667,"sku":"RA26043-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121336672435,"sku":"RA26043-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_730797a5-9144-4a49-95e5-97820b36ff57.png?v=1773346572","url":"https:\/\/afsbio.com\/products\/hp1%ce%b3-polyclonal-antibody-ra26043","provider":"AFSBio Inc.","version":"1.0","type":"link"}