{"product_id":"hpk1-rabbit-pab-es2564","title":"HPK1 rabbit pAb - ES2564","description":"\u003cp\u003eHPK1 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES2564-50, ES2564-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: catalytic activity:ATP + a protein = ADP + a phosphoprotein., cofactor:Magnesium., function:May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions and growth regulation., similarity:Belongs to the protein kinase superfamily. STE Ser\/Thr protein kinase family. STE20 subfamily., similarity:Contains 1 CNH domain., similarity:Contains 1 protein kinase domain., subunit:Interacts with MAP3K1., tissue specificity:Expressed primarily in hematopoietic organs, including bone marrow, spleen and thymus. Also expressed at very low levels in lung, kidney, mammary glands and small intestine.,\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: MAP4K1; HPK1; Mitogen-activated protein kinase kinase kinase kinase 1; Hematopoietic progenitor kinase; MAPK\/ERK kinase kinase kinase 1; MEK kinase kinase 1; MEKKK 1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human MEKKK 1. AA range:371-420\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 91kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 11184\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q92918\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: intracellular, cytoplasm, membrane,\u003c\/p\u003e \n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202085118131,"sku":"ES2564-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202085150899,"sku":"ES2564-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_42ec383e-12e9-4ec3-ba29-5fbe78f810ea.png?v=1767121520","url":"https:\/\/afsbio.com\/products\/hpk1-rabbit-pab-es2564","provider":"AFSBio Inc.","version":"1.0","type":"link"}