{"product_id":"hrp-conjugated-rabbit-anti-mouse-ige-fc-mab-as121","title":"HRP conjugated Rabbit Anti-Mouse IgE (Fc) mAb - AS121","description":"\u003cp\u003eHRP conjugated Rabbit Anti-Mouse IgE (Fc) mAb\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: AS121-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens 1, 2. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V- (D) -J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen\u003c\/p\u003e\n\n\u003cp\u003eCategory: Secondary Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Mouse (recombinant protein)\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: Refer to figures\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment).\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names:  Ig epsilon chain C region, Immunoglobulin heavy constant epsilon\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: ELISA, 1:5000-1:10000\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell membrane, Secreted.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: IGHE\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ARC60077-HRP\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"Default Title","offer_id":45190101303475,"sku":"AS121-100","price":77.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_fe7cc487-0304-4ae8-ba88-101f3c2bd758.png?v=1766442480","url":"https:\/\/afsbio.com\/products\/hrp-conjugated-rabbit-anti-mouse-ige-fc-mab-as121","provider":"AFSBio Inc.","version":"1.0","type":"link"}