{"product_id":"hrs-phospho-tyr216-rabbit-pab-es1329","title":"Hrs (phospho Tyr216) rabbit pAb - ES1329","description":"\u003cp\u003eHrs (phospho Tyr216) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES1329-50, ES1329-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq, Dec 2010],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: HGS; HRS; Hepatocyte growth factor-regulated tyrosine kinase substrate; Hrs; Protein pp110\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized phospho-peptide around the phosphorylation site of human Hrs (phospho Tyr216)\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 115kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 9146\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: O14964\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Endosome, multivesicular body membrane; Peripheral membrane protein. Colocalizes with UBQLN1 in ubiquitin-rich cytoplasmic aggregates that are not endocytic compartments.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202007589043,"sku":"ES1329-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202007621811,"sku":"ES1329-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_3339144a-a175-4d54-800a-4ce6c56d5d3f.png?v=1767119832","url":"https:\/\/afsbio.com\/products\/hrs-phospho-tyr216-rabbit-pab-es1329","provider":"AFSBio Inc.","version":"1.0","type":"link"}