{"product_id":"hsd3b7-polyclonal-antibody-e-ab-11311","title":"HSD3B7 Polyclonal Antibody - E-AB-11311","description":"\u003cp\u003eHSD3B7 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-11311-60, E-AB-11311-120, E-AB-11311-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: HSD3B7\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: 3 beta HSD VII; 3 beta hydroxy Delta(5) C27 steroid oxidoreductase; 3 beta hydroxysteroid dehydrogenase type 7; 3 beta hydroxysteroid dehydrogenase type VII; AI195443; BB098564; C(27) 3 beta HSD; Cca2; Cholest 5 ene 3 beta; 7 alpha diol 3 beta dehydrogenase; Confluent 3Y1 cell associated 2; Hydroxy delta 5 steroid dehydrogenase; 3 beta and steroid delta isomerase 7; OTTMUSP00000018894; OTTMUSP00000018895; OTTMUSP00000018897; PFIC4; SDR11E3\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9H2F3\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase\/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.3 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human HSD3B7\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"200μL","offer_id":43124079820979,"sku":"E-AB-11311-200","price":558.6,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43124079853747,"sku":"E-AB-11311-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"60μL","offer_id":43124079886515,"sku":"E-AB-11311-60","price":200.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_a5ce3147-14d6-4638-8970-2b931f10e866.png?v=1709723571","url":"https:\/\/afsbio.com\/products\/hsd3b7-polyclonal-antibody-e-ab-11311","provider":"AFSBio Inc.","version":"1.0","type":"link"}