{"product_id":"hsp105-rabbit-pab-es2580","title":"HSP105 rabbit pAb - ES2580","description":"\u003cp\u003eHSP105 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES2580-50, ES2580-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: function:Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8\/HSC70 ATPase and chaperone activities., PTM:Phosphorylation on Ser-509 may be important for regulation of the HSPA8\/HSC70 chaperone activity., similarity:Belongs to the heat shock protein 70 family., subunit:Interacts with HSPA8\/HSC70., tissue specificity:Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.,\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: HSPH1; HSP105; HSP110; KIAA0201; Heat shock protein 105 kDa; Antigen NY-CO-25; Heat shock 110 kDa protein\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human HSP105. AA range:791-840\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 100kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 10808\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q92598\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202086002867,"sku":"ES2580-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202086035635,"sku":"ES2580-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_dfa61aab-071d-4756-9747-91a39382b572.png?v=1767121542","url":"https:\/\/afsbio.com\/products\/hsp105-rabbit-pab-es2580","provider":"AFSBio Inc.","version":"1.0","type":"link"}