{"product_id":"htr2b-polyclonal-antibody-e-ab-92480","title":"HTR2B Polyclonal Antibody - E-AB-92480","description":"\u003cp\u003eHTR2B Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-92480-60, E-AB-92480-120, E-AB-92480-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: HTR2B\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: HTR2B; 5-HT(2B); 5-HT-2B; 5-HT2B\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Metabolism, Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P41595\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human HTR2B\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:200-1:1000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 54kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 54kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146636722355,"sku":"E-AB-92480-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146636755123,"sku":"E-AB-92480-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146636787891,"sku":"E-AB-92480-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_6a1f650c-89a5-4cce-9815-4fc39d88ac02.png?v=1710299019","url":"https:\/\/afsbio.com\/products\/htr2b-polyclonal-antibody-e-ab-92480","provider":"AFSBio Inc.","version":"1.0","type":"link"}