{"product_id":"htr2c-polyclonal-antibody-e-ab-90309","title":"HTR2C Polyclonal Antibody - E-AB-90309","description":"\u003cp\u003eHTR2C Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-90309-120, E-AB-90309-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: HTR2C\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: HTR2C; 5-HT1C; 5-HT2C; 5-HTR2C; 5HTR2C; HTR1C\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Metabolism, Neuroscience, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P28335\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human HTR2C\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:1000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 28kDa\/51kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 75kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"120μL","offer_id":43149050216627,"sku":"E-AB-90309-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43149050249395,"sku":"E-AB-90309-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_e6c2896b-5652-4fe4-b03c-e61e4c9ecb7c.png?v=1710339291","url":"https:\/\/afsbio.com\/products\/htr2c-polyclonal-antibody-e-ab-90309","provider":"AFSBio Inc.","version":"1.0","type":"link"}