{"product_id":"hxk-i-polyclonal-antibody-bt-ap04305","title":"HXK I Polyclonal Antibody - BT-AP04305","description":"\u003cp\u003eHXK I Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP04305-20, BT-AP04305-50, BT-AP04305-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. HK1 encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in HK1 have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HK1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: HXK I Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 102486\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P19367; Mouse: P17710; Rat: P05708\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: HK1; Hexokinase-1; Brain form hexokinase; Hexokinase type I; HK I\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3098; Rat: 25058\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240383570099,"sku":"BT-AP04305-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240383602867,"sku":"BT-AP04305-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240383635635,"sku":"BT-AP04305-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_7fb31d1e-3ed3-46f5-b696-622fcde072c1.png?v=1769407674","url":"https:\/\/afsbio.com\/products\/hxk-i-polyclonal-antibody-bt-ap04305","provider":"AFSBio Inc.","version":"1.0","type":"link"}