{"product_id":"hxk-ii-monoclonal-antibody-bt-mca0761","title":"HXK II Monoclonal Antibody - BT-MCA0761","description":"\u003cp\u003eHXK II Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA0761-50, BT-MCA0761-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction; Cancer; Metabolism; Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: HK2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human,Mouse,Rat,Pig\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Hexokinase-2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P52789; Mouse: O08528; Rat: P27881\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: HK2; Hexokinase-2; Hexokinase type II; HK II; Muscle form hexokinase\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3099; Mouse: 15277; Rat: 25059\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238716760243,"sku":"BT-MCA0761-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238716793011,"sku":"BT-MCA0761-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_be19d534-e705-4239-b1c2-926ccbc227d3.png?v=1769384052","url":"https:\/\/afsbio.com\/products\/hxk-ii-monoclonal-antibody-bt-mca0761","provider":"AFSBio Inc.","version":"1.0","type":"link"}