{"product_id":"hydrogen-exchanger-3-polyclonal-antibody-bs65548","title":"hydrogen exchanger 3 Polyclonal Antibody-BS65548","description":"hydrogen exchanger 3 Polyclonal Antibody\n\nSizes: 50µl, 100µl\n\nCatalogue Numbers: BS65548-50, BS65548-100\n\nProduct: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\n\nSwiss-Prot: P48764\n\nHost: Rabbit\n\nReactivity: Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep,\n\nApplications: WB\n\nAll Applications: WB=1:500-2000 \nnot yet tested in other applications.\noptimal dilutions\/concentrations should be determined by the end user.\n\nBackground: NHE-3 are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions. While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics. NHE-3 localizes to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption. NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly. NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells.\n\nPurification and Purity: affinity purified by Protein A\n\nStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\n\nSpecificity: hydrogen exchanger 3 polyclonal Antibody detects endogenous levels of hydrogen exchanger 3 protein.\n\nBioworld Molecular Weight: ~80kDa\n\nNote: For research use only, not for use in diagnostic procedure.\n\nExtra Notes: Anti-hydrogen exchanger 3 at 1\/1000 dilution\n\nAlternative Name: Na(+)\/H(+) exchanger 3; NHE 3; NHE-3; NHE3; SL9A3_HUMAN; SLC9A 3; Sodium; Slc9a3; Sodium\/hydrogen exchanger 3; Sodium\/hydrogen exchanger, apical epithelial; Solute carrier family 9 (sodium\/hydrogen exchanger), isoform 3; Solute carrier family 9 (sodium\/hydrogen exchanger), member 3; Solute carrier family 9 member 3; MGC126718; MGC126720. \n\nImmunogen: KLH conjugated synthetic peptide derived from human hydrogen exchanger 3 :581-680\/834 \u003ccytoplasmic\u003e\n\nConjugate: Unconjugated\n\nModification: Unmodified\u003c\/cytoplasmic\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43029540667571,"sku":"BS65548-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43029540700339,"sku":"BS65548-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_ce451f18-123c-4baa-b1e5-a53b57a2cf1d.jpg?v=1707221397","url":"https:\/\/afsbio.com\/products\/hydrogen-exchanger-3-polyclonal-antibody-bs65548","provider":"AFSBio Inc.","version":"1.0","type":"link"}