{"product_id":"iκb-α-polyclonal-antibody-ra30715","title":"IκB-α Polyclonal Antibody - RA30715","description":"\u003cp\u003eIκB-α Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA30715-50, RA30715-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: NFKB inhibitor alpha (NFKBIA) Homo sapiens This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B\/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011],\u003c\/p\u003e\n\n\u003cp\u003eCondition: PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB: 1:2000-5000 IHC: 1:200-500\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: NFKBIA; IKBA; MAD3; NFKBI; NF-kappa-B inhibitor alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3; YM3423\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC-p; IF (paraffin section)\u003c\/p\u003e \n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 4792\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 40\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P25963\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45122450882739,"sku":"RA30715-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45122450915507,"sku":"RA30715-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_4300c12c-5544-4a60-a4c9-becd4f84731e.png?v=1773349045","url":"https:\/\/afsbio.com\/products\/i%ce%bab-%ce%b1-polyclonal-antibody-ra30715","provider":"AFSBio Inc.","version":"1.0","type":"link"}