{"product_id":"i-kappa-b-alpha-monoclonal-antibody-bt-mca0792","title":"I Kappa B- Alpha Monoclonal Antibody - BT-MCA0792","description":"\u003cp\u003eI Kappa B- Alpha Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA0792-50, BT-MCA0792-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B\/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction; Neuroscience; Epigenetics and nuclear signaling; Cancer; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NFKBIA\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human,Mouse,Rat,Pig,sheep\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: NF-kappa-B inhibitor alpha\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P25963; Mouse: Q9Z1E3; Rat: Q63746\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: NFKBIA; IKBA; MAD3; NFKBI; NF-kappa-B inhibitor alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 4792; Mouse: 18035; Rat: 25493\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238719938739,"sku":"BT-MCA0792-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238719971507,"sku":"BT-MCA0792-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_9555ab39-a47e-4471-ad04-0f84538b4a46.png?v=1769384089","url":"https:\/\/afsbio.com\/products\/i-kappa-b-alpha-monoclonal-antibody-bt-mca0792","provider":"AFSBio Inc.","version":"1.0","type":"link"}