{"product_id":"i12r2-polyclonal-antibody-ra32720","title":"I12R2 Polyclonal Antibody - RA32720","description":"I12R2 Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA32720-50, RA32720-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: interleukin 12 receptor subunit beta 2 (IL12RB2) Homo sapiens The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene. [provided by RefSeq, Apr 2012],\n\nCondition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: WB 1:500-2000 ELISA 1:5000-20000\n\nApplications: WB; ELISA\n\nSpecies Cross-Reactivity: Human; Mouse\n\nGeneID (Human): 3595\n\nProtein MW (KDa): 94\n\nSWISS: Q99665\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120485687475,"sku":"RA32720-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120485720243,"sku":"RA32720-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ccad6ca2-cc55-43a9-946a-614a577860ad.png?v=1773366477","url":"https:\/\/afsbio.com\/products\/i12r2-polyclonal-antibody-ra32720","provider":"AFSBio Inc.","version":"1.0","type":"link"}