{"product_id":"i27ra-polyclonal-antibody-bt-ap10259","title":"I27RA Polyclonal Antibody - BT-AP10259","description":"\u003cp\u003eI27RA Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP10259-20, BT-AP10259-50, BT-AP10259-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Immunology; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: IL27RA\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Interleukin-27 receptor subunit alpha\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q6UWB1; Mouse: O70394\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Interleukin-27 receptor subunit alpha;IL-27 receptor subunit alpha;IL-27R subunit alpha;IL-27R-alpha;IL-27RA;Cytokine receptor-like 1;Type I T-cell cytokine receptor;TCCR;WSX-1;ZcytoR\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 9466\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239176003763,"sku":"BT-AP10259-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239176036531,"sku":"BT-AP10259-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239176069299,"sku":"BT-AP10259-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_734a49c2-4a72-40d4-b025-7ca9601884a7.png?v=1769390175","url":"https:\/\/afsbio.com\/products\/i27ra-polyclonal-antibody-bt-ap10259","provider":"AFSBio Inc.","version":"1.0","type":"link"}