{"product_id":"ide-insulin-degrading-enzyme-mouse-mab-em1083","title":"IDE\/Insulin Degrading Enzyme Mouse mAb - EM1083","description":"\u003cp\u003eIDE\/Insulin Degrading Enzyme Mouse mAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: EM1083-50, EM1083-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Name: Abeta degrading protease, insulin degrading enzyme, Insulin protease, Insulinase, INSULYSIN\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:1, 000 IHC 1:200\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic Peptide\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG1\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 118kDa\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 3416\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P14735\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell membrane,  Cytoplasm,  Membrane,  Secreted\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201988812979,"sku":"EM1083-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201988845747,"sku":"EM1083-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_3375146a-f08c-48c8-9cb4-0338120a70b1.png?v=1767119434","url":"https:\/\/afsbio.com\/products\/ide-insulin-degrading-enzyme-mouse-mab-em1083","provider":"AFSBio Inc.","version":"1.0","type":"link"}