{"product_id":"idh2-monoclonal-antibody-bt-mca3248","title":"IDH2 Monoclonal Antibody - BT-MCA3248","description":"\u003cp\u003eIDH2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3248-50, BT-MCA3248-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Metabolism, Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: IDH2\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 3E8E9\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: IDH2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human IDH2 (AA: 1-143) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 50.9kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P48735\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: IDH, IDP, IDHM, IDPM, ICD-M, D2HGA2, mNADP-IDH\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3418\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238526902451,"sku":"BT-MCA3248-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238526935219,"sku":"BT-MCA3248-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_0c381ada-d93c-4863-960a-9f38992e94d7.png?v=1769382245","url":"https:\/\/afsbio.com\/products\/idh2-monoclonal-antibody-bt-mca3248","provider":"AFSBio Inc.","version":"1.0","type":"link"}