{"product_id":"idh2-polyclonal-antibody-e-ab-15121","title":"IDH2 Polyclonal Antibody - E-AB-15121","description":"\u003cp\u003eIDH2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-15121-60, E-AB-15121-120, E-AB-15121-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: IDH2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: D2HGA2; ICD-M; IDH; IDH2; IDHM; IDHP; IDP; IDPM; Isocitrate dehydrogenase [NADP]; mitochondrial; Isocitrate dehydrogenase 2 (NADP+); mitochondrial; mNADP-IDH; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Metabolism, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P48735\u003c\/p\u003e\n\n\u003cp\u003eBackground: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.4 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human IDH2\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IHC 1:100-1:300\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 51kDa\u003c\/p\u003e\n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43141468618931,"sku":"E-AB-15121-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43141468651699,"sku":"E-AB-15121-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43141468684467,"sku":"E-AB-15121-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_c22ab8db-b0b5-45ab-8cf4-7085f6e09de8.png?v=1710156218","url":"https:\/\/afsbio.com\/products\/idh2-polyclonal-antibody-e-ab-15121","provider":"AFSBio Inc.","version":"1.0","type":"link"}