{"product_id":"ifi-16-n772-polyclonal-antibody-bs3865","title":"IFI-16 (N772) Polyclonal Antibody - BS3865","description":"\u003cp\u003eIFI-16 (N772) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS3865-50, BS3865-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: Interferon-gamma inducible protein 16 (IFI16) belongs to the HIN-200 family of transcriptional regμlator linked to cell cycle regμlation and differentiation by modμlating the activities of mμltiple transcriptional factors, such as p53 and Rb. The HIN-200 (hematopoeitic interferon-inducible nuclear antigens with 200 amino acid repeat) family members contain a DNA binding domain, a transcriptional regμlatory domain, DAPIN\/PAAD domain associated with interferon response and a binding domain for BRCA1. IFI16 may have a role in the regμlation of hematopoeitic cell differentiation and also be involved in DNA repair since it becomes a component of the DNA repair mμlti-protein BASC complex after UV-induced DNA damage. IFI16 is strongly induced by gamma interferon in vivo.\u003c\/p\u003e \n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Gamma-interferon-inducible protein Ifi-16, Interferon-inducible myeloid differentiation transcriptional activator, IFI16, IFNGIP1\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodification\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 740-795 of Human IFI-16.\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IFI-16 (N772) polyclonal antibody detects endogenous levels of IFI-16 protein.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 88 kDa\u003c\/p\u003e\n\n\u003cp\u003ePathway: Inflammasonme Signaling,\u003c\/p\u003e \n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: Q16666\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45946261471411,"sku":"BS3865-50","price":274.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45946261504179,"sku":"BS3865-100","price":457.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_6ca33534-2486-4e91-ac84-9e0d75778258.jpg?v=1788363539","url":"https:\/\/afsbio.com\/products\/ifi-16-n772-polyclonal-antibody-bs3865","provider":"AFSBio Inc.","version":"1.0","type":"link"}