{"product_id":"ifn-γ-q69-polyclonal-antibody-bs3486","title":"IFN-γ (Q69) Polyclonal Antibody-BS3486","description":"\u003cp\u003eIFN-γ (Q69) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS3486-50, BS3486-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P01579\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IP,\u003c\/p\u003e  \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003cbr\u003e\nIHC: 1:50~1:200\u003cbr\u003e\nIP: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Interferon (IFN)-γ is an antiviral and antiparasitic agent produced by CD4+\/CD8+ lymphocytes and natural killer cells that undergo activation by antigens, mitogens or alloantigens. IFN-γ production modulates T cell growth and differentiation and inhibits the growth of B cells. Synthesis of IFN-γ is inducible by IL-2, FGF and EGF. The active form of IFN-γ is a homodimer with each subunit containing six helices. The dimeric structure of human IFN-γ is stabilized by non-covalent interactions through the interface of the helices. IFN-γ tranlsated precursor is 166 amino acids, including the 23 amino acid secretory sequence. Multiple forms exist due to variable glycosylation and under non-denaturing conditions due to dimers and tetramers.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IFN-γ (Q69) polyclonal antibody detects endogenous levels of IFN-γ protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 19 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of IFN-γ (Q69) polyclonal antibody at 1:500 dilution\u003cbr\u003e\n Lane 1: HEK293T whole cell lysate\u003cbr\u003e\n Lane 2: Raw264.7 whole cell lysate\u003cbr\u003e\n Lane 3: H9C2 whole cell lysate, Immunohistochemistry (IHC) analyzes of IFN-γ (Q69) pAb in paraffin-embedded human lymph node tissue., Immunoprecipitation of the Spleen tissue lysate of Rat using IFN-γ (Q69) pAb (Sepharose Bead Conjugate) #BD0047(Lane 2 and Lane 3) and Nonspecific IgG Control (Sepharose Bead Conjugate)#BD0047 (Lane 4 and Lane 5). Lane 1 is 30% input. The western blot was probed using IFN-γ (Q69) pAb #BS3486. “↑”(supernatant); “↓”(deposition)\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: IFN-gamma; Immune interferon; IFN-gamma . Interferon gamma; IFNG; IFNγ\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 31-80 of Human IFN-γ.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42993798152371,"sku":"BS3486-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42993798185139,"sku":"BS3486-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_0d4fed83-86a4-4cbd-a7c6-8b37fe171842.jpg?v=1706183678","url":"https:\/\/afsbio.com\/products\/ifn-%ce%b3-q69-polyclonal-antibody-bs3486","provider":"AFSBio Inc.","version":"1.0","type":"link"}