{"product_id":"ifn-alpha-1-monoclonal-antibody-mb66766","title":"IFN alpha 1 Monoclonal Antibody-MB66766","description":"\u003cp\u003eIFN alpha 1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB66766-50, MB66766-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P01562\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB (1\/500 - 1\/1000)\u003c\/p\u003e\n\n\u003cp\u003eBackground: The genes encoding type I interferons (IFNs), which include 14 IFN-a genes, one IFN-β gene, one IFN-w (also known as IFN-a II1) gene, and a number of IFN-w pseudogenes, are clustered on human chromosome 9. Interferon-a and -β are cytokines that are widely known to induce potent antiviral activity. They exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-a, IFN-β or IFN-g, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt’s lymphoma cells. The type I interferon receptor (IFN-aR) interacts with IFN-a, IFN-β and IFN-w, and seems to be a multisubunit receptor.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: This antibody is purified through a protein G column.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Recognizes endogenous levels of IFN alpha 1 protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of IFN alpha 1 expression in IFN (A) whole cell lysates.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 17 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Interferon alpha-1\/13; IFN-alpha-1\/13; Interferon alpha-D; LeIF D\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human IFN alpha 1. The exact sequence is proprietary.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42906375389363,"sku":"MB66766-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42906375422131,"sku":"MB66766-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_3286faf9-58e2-4694-b850-dec307decd21.jpg?v=1702918873","url":"https:\/\/afsbio.com\/products\/ifn-alpha-1-monoclonal-antibody-mb66766","provider":"AFSBio Inc.","version":"1.0","type":"link"}