{"product_id":"ifn-alpha-beta-ralpha-polyclonal-antibody-bt-ap08691","title":"IFN-alpha\/beta RAlpha Polyclonal Antibody - BT-AP08691","description":"\u003cp\u003eIFN-alpha\/beta RAlpha Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP08691-20, BT-AP08691-50, BT-AP08691-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases| which in turn phosphorylate several proteins| including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Immunology; Epigenetics and nuclear signaling; Signal transduction; Cancer\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: IFNAR1\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Interferon alpha\/beta receptor 1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P17181; Mouse: P33896\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Interferon alpha\/beta receptor 1 (IFN-R-1;IFN-alpha\/beta receptor 1;Cytokine receptor class-II member 1;Cytokine receptor family 2 member 1;CRF2-1;Type I interferon receptor 1); Interferon alpha\/beta receptor 1; IFN-R-1; IFN-alpha\/beta receptor 1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; CRF2-1; Type I interferon receptor 1)\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3454; Mouse: 15975\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45238983524531,"sku":"BT-AP08691-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45238983557299,"sku":"BT-AP08691-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238983590067,"sku":"BT-AP08691-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_115670f0-a31e-447e-b699-69271efe9a6d.png?v=1769387551","url":"https:\/\/afsbio.com\/products\/ifn-alpha-beta-ralpha-polyclonal-antibody-bt-ap08691","provider":"AFSBio Inc.","version":"1.0","type":"link"}