{"product_id":"ifn-beta-monoclonal-antibody-mb66767","title":"IFN beta Monoclonal Antibody-MB66767","description":"\u003cp\u003eIFN beta Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB66767-50, MB66767-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P01574\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB (1\/500 - 1\/1000)\u003c\/p\u003e\n\n\u003cp\u003eBackground: The genes encoding type I interferons (IFNs), which include 14 IFN-α genes, one IFN-β gene, one IFN-ω (also known as IFN-α II1) gene and a number of IFN-ω pseudogenes, are clustered on human chromosome 9. IFN-α and -β are cytokines that are widely known to induce potent antiviral activity. They exert a variety of other biological effects, including antitumor and immunomodulatory activities, and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-ω is antigenically different from human IFN-α, IFN-β or IFN-g, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt’s lymphoma cells. The type I interferon receptor (IFN-αR) interacts with IFN-α, IFN-β and IFN-ω, and seems to be a multisubunit receptor.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: This antibody is purified through a protein G column.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Recognizes endogenous levels of IFN beta protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of IFN beta expression in IFNB1 protein (A) whole cell lysates.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 24 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: IFB; IFNB; Interferon beta; IFN-beta; Fibroblast interferon\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human IFN beta. The exact sequence is proprietary.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42906375520435,"sku":"MB66767-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42906375553203,"sku":"MB66767-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_70e6c851-a74c-44c2-a2c2-b50838dfbd2e.jpg?v=1702918875","url":"https:\/\/afsbio.com\/products\/ifn-beta-monoclonal-antibody-mb66767","provider":"AFSBio Inc.","version":"1.0","type":"link"}