{"product_id":"ifn-beta-polyclonal-antibody-bt-ap02022","title":"IFN-beta Polyclonal Antibody - BT-AP02022","description":"\u003cp\u003eIFN-beta Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP02022-20, BT-AP02022-50, BT-AP02022-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a cytokine that belongs to the interferon family of signaling proteins| which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons| which are important for defense against viral infections. In addition| type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen| type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Immunology; Cardiovascular; Cell biology; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: IFNB1\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Interferon beta\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P01574; Mouse: P01575\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Interferon beta (IFN-beta;Fibroblast interferon); Interferon beta; IFN-beta; Fibroblast interferon)\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 3456; Mouse: 15977\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45238983622835,"sku":"BT-AP02022-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45238983655603,"sku":"BT-AP02022-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238983688371,"sku":"BT-AP02022-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_139c6023-b856-4e94-8b70-1e77a02eb9dd.png?v=1769387552","url":"https:\/\/afsbio.com\/products\/ifn-beta-polyclonal-antibody-bt-ap02022","provider":"AFSBio Inc.","version":"1.0","type":"link"}