{"product_id":"ifn-gamma-monoclonal-antibody-bt-mca3038","title":"IFN-gamma Monoclonal Antibody - BT-MCA3038","description":"\u003cp\u003eIFN-gamma Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3038-50, BT-MCA3038-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Interferon-G (IFN-G) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainly produced by natural killer cells and CD4+ and CD8+ T cells, its receptors are found on nearly all cells, where it activates diverse responses that enable potential host cells to prevent invasive infection by bacteria, parasites and viruses. Takayanagi et al. (2000) demonstrated that IFN-G strongly suppresses osteoclastogenesis by interfering with the RANKL (602642)-RANK (603499) signaling pathway. Tsubota et al. (1999) reported that this upregulation in Sjogren syndrome patients may be controlled by interferon-gamma through the activation of transcription factor NFKB\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: IFN-gamma\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 3F1E3\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: IFN-gamma\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human IFN-γ expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 19.3kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P01579\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: IFG, IFI\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3458\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238428926131,"sku":"BT-MCA3038-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238428958899,"sku":"BT-MCA3038-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e9b6b770-d8d6-4913-a13d-68ce900b7aa0.png?v=1769380671","url":"https:\/\/afsbio.com\/products\/ifn-gamma-monoclonal-antibody-bt-mca3038","provider":"AFSBio Inc.","version":"1.0","type":"link"}