{"product_id":"ifn-r1-polyclonal-antibody-bs7140","title":"IFN-R1 Polyclonal Antibody-BS7140","description":"\u003cp\u003eIFN-R1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS7140-50, BS7140-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P17181\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIFN-R1 Polyclonal Antibody-BS7140\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:500~1:2000\u003cbr\u003e\nIHC: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: The type I interferons, IFN-α and IFN-β, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-α and IFN-β appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-γ) binds to a distinct receptor. This distinct receptor, IFN-αR, is only weakly responsive to type I interferons, in contrast to IFN-α\/βR, which binds to and responds effectively to IFN-β and to several of the IFN-α subtypes. IFN-α\/βR is expressed as two alternatively spliced transcripts, designated IFN-α\/βRα (IFN-α\/βR1) and IFN-α\/βRβ (IFN- α\/βR2), both of which are involved in signal transduction and ligand binding.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IFN-R1 polyclonal antibody detects endogenous levels of IFN-R1 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 64 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of IFN-R1 polyclonal antibody, Immunohistochemistry (IHC) analysis of IFN-R1 polyclonal antibody in paraffin-embedded Human Liver Cancer tissue.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Interferon alpha\/beta receptor 1; IFN-R-1; IFN-alpha\/beta receptor 1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; CRF2-1; Type I interferon receptor 1; IFNAR1; IFNAR; IFNR1; IFN R1; IFN-α\/βRα; IFN-α\/βR1; IFN α\/βRα; IFNα\/βR1; IFNα\/β-Rα; IFNα\/β R1;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Recombinant full length Human IFN-R1.\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42962813354163,"sku":"BS7140-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42962813386931,"sku":"BS7140-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_860fc526-9c16-44d5-84cb-59635cfacac6.jpg?v=1705319087","url":"https:\/\/afsbio.com\/products\/ifn-r1-polyclonal-antibody-bs7140","provider":"AFSBio Inc.","version":"1.0","type":"link"}