{"product_id":"ifn-r1-rabbit-monoclonal-antibody-bs9863m","title":"IFN-R1 Rabbit Monoclonal Antibody-BS9863M","description":"\u003cp\u003eIFN-R1 Rabbit Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS9863M-50, BS9863M-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P17181\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC FC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:1000-1:2000 \u003cbr\u003e\nIHC: 1:50-1:200\u003cbr\u003e\nFC: 1:50-1:100\u003c\/p\u003e\n\n\u003cp\u003eBackground: The type I interferons, IFN-α and IFN-β, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-α and IFN-β appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-γ) binds to a distinct receptor. This distinct receptor, IFN-αR, is only weakly responsive to type I interferons, in contrast to IFN-α\/βR, which binds to and responds effectively to IFN-β and to several of the IFN-α subtypes. IFN-α\/βR is expressed as two alternatively spliced transcripts, designated IFN-α\/βRα (IFN-α\/βR1) and IFN-α\/βRβ (IFN- α\/βR2), both of which are involved in signal transduction and ligand binding.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Protein A affinity purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: This antibody detects endogenous levels of IFN-R1 and does not cross-react with related proteins.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 50 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-IFN-R1 antibody. Counter stained with hematoxylin, Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-IFN-R1 antibody. Counter stained with hematoxylin., Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-IFN-R1 antibody. Counter stained with hematoxylin\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Interferon alpha\/beta receptor 1; IFN-R-1; IFN-alpha\/beta receptor 1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; CRF2-1; Type I interferon receptor 1; IFNAR1; IFNAR; IFNR1; IFN R1; IFN-α\/βRα; IFN-α\/βR1; IFN α\/βRα; IFNα\/βR1; IFNα\/β-Rα; IFNα\/β R1;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Recombinant antibody.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43004765372595,"sku":"BS9863M-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43004765405363,"sku":"BS9863M-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_b5a55a55-ff33-4e83-8d78-d20b56c825b1.jpg?v=1706446007","url":"https:\/\/afsbio.com\/products\/ifn-r1-rabbit-monoclonal-antibody-bs9863m","provider":"AFSBio Inc.","version":"1.0","type":"link"}