{"product_id":"ifnb1-polyclonal-antibody-bs60295","title":"IFNB1 Polyclonal Antibody-BS60295","description":"\u003cp\u003eIFNB1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS60295-50, BS60295-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Interferon beta; Interferon β; IFN-beta; IFN-β; IFNβ; Fibroblast interferon; IFB; IFNB\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P01574\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: The genes encoding type I interferons (IFNs), which include 14 IFN-α genes, one IFN-β gene, one IFN-w (also known as IFN-α II1) gene, and a number of IFN-w pseudogenes, are clustered on human chromosome 9. Interferons-α and -β are cytokines that are widely known to induce potent antiviral activity. IFN-α and -β exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-α, IFN-β or IFN-γ, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-αR) interacts with IFN-α, IFN-β and IFN-w, and seems to be a multisubunit receptor.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IFNB1 polyclonal antibody detects endogenous levels of IFNB1 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 26 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of IFNB1 polyclonal antibody at 1:500 dilution\u003cbr\u003e\nLane 1: MCF-7 cell lysate\u003cbr\u003e\nLane 2: Mouse liver tissue lysate\u003cbr\u003e\nLane 3: Rat liver tissue lysate\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide corresponding to residues in Human IFNB1.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42913552072883,"sku":"BS60295-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42913552105651,"sku":"BS60295-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_ec5a8ef4-ce99-491f-9d39-9e9c15023390.jpg?v=1703266333","url":"https:\/\/afsbio.com\/products\/ifnb1-polyclonal-antibody-bs60295","provider":"AFSBio Inc.","version":"1.0","type":"link"}