{"product_id":"igf-i-receptor-β-phospho-tyr1131-rabbit-polyclonal-antibody-ra26193","title":"IGF-I Receptor β (phospho-Tyr1131) Rabbit Polyclonal Antibody - RA26193","description":"\u003cp\u003eIGF-I Receptor β (phospho-Tyr1131) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA26193-50, RA26193-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: insulin like growth factor 1 receptor (IGF1R) Homo sapiens This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB 1:1000-2000\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 3480\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 155\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P08069\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121343717555,"sku":"RA26193-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121343750323,"sku":"RA26193-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_4760a10c-0a70-42fc-9e56-890e2475b535.png?v=1773346648","url":"https:\/\/afsbio.com\/products\/igf-i-receptor-%ce%b2-phospho-tyr1131-rabbit-polyclonal-antibody-ra26193","provider":"AFSBio Inc.","version":"1.0","type":"link"}