{"product_id":"igf-ir-monoclonal-antibody-ra11495","title":"IGF-IR Monoclonal Antibody - RA11495","description":"\u003cp\u003eIGF-IR Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSize: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA11495-50, RA11495-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: insulin like growth factor 1 receptor (IGF1R) Homo sapiens This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC-p; IF (paraffin section) ; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 3480\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P08069\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45118977999027,"sku":"RA11495-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45118978031795,"sku":"RA11495-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_da84db51-6a58-460f-8e47-da396c46fa80.png?v=1773343846","url":"https:\/\/afsbio.com\/products\/igf-ir-monoclonal-antibody-ra11495","provider":"AFSBio Inc.","version":"1.0","type":"link"}