{"product_id":"igll1-polyclonal-antibody-e-ab-19173","title":"IGLL1 Polyclonal Antibody - E-AB-19173","description":"\u003cp\u003eIGLL1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-19173-60, E-AB-19173-120, E-AB-19173-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: IGLL1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: 14.1; AGM2; CD179 antigen-like family member B; CD179b; CD179b antigen; Ig lambda 5; Ig lambda-5; IGL1; IGL5; IGLJ14.1; IGLL; Igll1; IGLL1; IGO; IGVPB; Immunoglobulin lambda like polypeptide 1 precursor; Immunoglobulin lambda-like polypeptide 1; Immunoglobulin omega polypeptide; Immunoglobulin omega polypeptide chain; Immunoglobulin related protein 14.1; Immunoglobulin-related protein 14.1; Lambda5; Pre B lymphocyte specific protein 2; VPREB2\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P15814\u003c\/p\u003e\n\n\u003cp\u003eBackground: The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.IGLL1 (Immunoglobulin Lambda Like Polypeptide 1) is a Protein Coding gene. Diseases associated with IGLL1 include Agammaglobulinemia 2 and Agammaglobulinemia, Non-Bruton Type. Among its related pathways are Cell surface interactions at the vascular wall and Primary immunodeficiency. An important paralog of this gene is IGLL5.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1.14 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Fusion protein of human IGLL1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:200, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43130752499891,"sku":"E-AB-19173-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43130752532659,"sku":"E-AB-19173-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43130752565427,"sku":"E-AB-19173-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_986ec62f-0979-493c-9a6a-2f8bbe516fcc.png?v=1709812210","url":"https:\/\/afsbio.com\/products\/igll1-polyclonal-antibody-e-ab-19173","provider":"AFSBio Inc.","version":"1.0","type":"link"}